NUMERO: #20240939

Título: AGRESSIVE ADENOID AMELOBLASTOMA IN THE MANDIBLE: A CASE REPORT

Nome do Apresentador: Amanda Almeida LEITE

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Patologia Oral

Resumo: A 61-year-old male was referred for assessment of a right-sided facial swelling of 3-month duration. His medical history included a prior partial mandibulectomy with histopathological diagnosis of ameloblastoma 5 years ago. Clinical examination revealed a significant swelling in the right mandible with spontaneous pain. Computed tomography identified a well-defined hypodense lesion located within the soft tissues of the floor of the mouth, involving the sublingual and submandibular spaces, measuring 11 x 10 x 9.5 cm. Surgical resection of residual mandible and soft tissues was performed. Microscopic analysis demonstrated a solid cellular proliferation characterized by peripheral cells displaying ameloblastic-like differentiation. Additionally, a cribriform arrangement with duct-like spaces, whorled cellular condensations, and dentinoid formation were observed. Nuclear positivity for β-catenin confirmed the diagnosis of adenoid ameloblastoma. Ki-67 was positive in <5% of tumor cells. Currently, the patient is under regular follow-up and no signs of recurrence were observed.

Autor 1:  Amanda Almeida LEITE

E-mail 1:  [email protected]

Autor 2:   Roberta Karolina Borges de SOUZA

E-mail 2:  [email protected]

Autor 3 :  Hélen Kaline Farias BEZERRA

E-mail 3:  [email protected]

Autor 4:  Elaine Judite de Amorim CARVALHO

E-mail 4:  [email protected]

Autor 5:  Carla Isabelly Rodrigues FERNANDES

E-mail 5:  [email protected]

Autor 6:  Pablo Agustin VARGAS

E-mail 6:  [email protected]

Autor 7:  Danyel Elias da Cruz PEREZ

E-mail 7:  [email protected]