NUMERO: #20240896

Título: The importance of follow-up of graft-versus-host disease in a young patient after halogen transplantation: case report

Nome do Apresentador: Matheus Henrique Alves de LIMA

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Oncologia

Resumo: Graft-versus-host disease (GVHD) is one of the most common complications in halogen hematopoietic stem cell transplantation patients. This disease may manifest in the oral mucosa and increases the risk for oral cancer. The aim of this study is report a case of GVHD oral manifestation. A 27-year-old male patient, after halogen transplantation due to medullary aplasia was referred to the stomatology department for evaluation of oral lesions. On extraoral examination, alopecia and facial vitiligo were observed. On intraoral examination, areas of epithelial atrophy on the dorsum of the tongue and an asymptomatic non-detachable homogeneous white plaque, measuring 2x2,5cm, were also observed. An incisional biopsy was performed and the histological analysis confirmed the GVHD. The patient was referred to the hematologist for evaluation and treatment. This case emphasizes the importance of a close follow-up by a multidisciplinary team to intercept oral manifestations of GVHD, reducing the risk for oral cancer.

Autor 1:  Matheus Henrique Alves de LIMA

E-mail 1:  [email protected]

Autor 2:   Catarina Rodrigues Rosa de OLIVEIRA

E-mail 2:  [email protected]

Autor 3 :  Robbysson Cayke de Sousa PEREIRA

E-mail 3:  [email protected]

Autor 4:  Renata D Andrada Tenório Almeida SILVA

E-mail 4:  [email protected]

Autor 5:  Glória Maria de FRANÇA

E-mail 5:  [email protected]

Autor 6:  Fabio Abreu ALVES

E-mail 6:  [email protected]

Autor 7:  Sonia Maria Soares FERREIRA

E-mail 7:  [email protected]