NUMERO: #20240860

Título: Characterization of Microbial Communities Associated with Dental Implants in a Patient with Osteoradionecrosis Lesion

Nome do Apresentador: Aljomar José VECHIATO FILHO

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Áreas afins no caráter multidisciplinar

Resumo: Osteoradionecrosis (ORN) lesion, a significant late toxicity associated with radiotherapy for head and neck cancer, may serve as a suitable habitat for the accumulation of important oral pathogens, which may increase the risk of implant-related infections and rehabilitation failures in patients with dental implants. This clinical report assessed the microbial profile on the ORN lesion, the dental implant located adjacent to the lesion and in the contralateral area, and the saliva of a patient attended dental service from a public cancer institute. The patient was subjected to surgical debridement of ORN but it persisted. ORN presence may be a risk factor for triggering biofilm-related oral infections as it serves as microbial reservoirs. Besides, implant adjacent to necrotic bone tissue showed notably higher levels of putative pathogen, which may source pathogenic microorganisms that will colonize the surface of the health bone tissue after ORN debridement.

Autor 1:  Aljomar José VECHIATO FILHO

E-mail 1:  [email protected]

Autor 2:   Maria Cláudia CUZZULLIN

E-mail 2:  [email protected]

Autor 3 :  Ana Leticia MORES

E-mail 3:  [email protected]

Autor 4:  Thaís Bianca BRANDÃO

E-mail 4:  [email protected]

Autor 5:  Valentim Adelino Ricardo BARÃO

E-mail 5:  [email protected]

Autor 6:  Ana Carolina Prado Ribeiro e SILVA

E-mail 6:  [email protected]

Autor 7:  Joã

E-mail 7:  o Gabriel Silva SOUZA