NUMERO: #20240797

Título: LARGE SOLITARY NEUROFIBROMA OF THE TONGUE: CASE REPORT

Nome do Apresentador: Natália Vitória de Araújo LOPES

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Patologia Oral

Resumo: Neurofibroma, a benign peripheral nerve neoplasm that can arise as a solitary tumor or be a component of neurofibromatosis, is uncommon in the oral cavity. A 28-year-old man was referred for evaluation of a slow-growing swelling in the tongue, that evolved over an approximately 14-year period. Intraoral examination revealed a firm, irregular, pinkish to yellowish nodular mass in the tongue, extending from ventral surface to dorsum, measuring approximately 5 cm. Considering the diagnostic hypothesis of mesenchymal neoplasm, an incisional biopsy was performed. Histopathologic analysis disclosed proliferation of spindle-shaped cells interspersed with collagen bundles and variable amounts of myxoid matrix. Immunohistochemical analysis revealed positivity for S-100 protein in most spindle-shaped cells and low proliferation index (Ki-67 < 5%). These findings were consistent with the diagnosis of neurofibroma. Treatment consisted of surgical excision and the previous histopathologic diagnosis was confirmed. No signs of recurrence were detected after 4 months of clinical follow-up.

Autor 1:  Natália Vitória de Araújo LOPES

E-mail 1:  [email protected]

Autor 2:   Júlia Brunner Uchôa Dantas MOREIRA

E-mail 2:  [email protected]

Autor 3 :  Raquel Vieira BEZERRA

E-mail 3:  [email protected]

Autor 4:  José Wilson Noleto RAMOS JUNIOR

E-mail 4:  [email protected]

Autor 5:  Daliana Queiroga de Castro GOMES

E-mail 5:  [email protected]

Autor 6:  Pollianna Muniz ALVES

E-mail 6:  [email protected]

Autor 7:  Cassiano Francisco Weege NONAKA

E-mail 7:  [email protected]