NUMERO: #20240749

Título: SQUAMOUS BASALOID CARCINOMA IN THE BASE OF THE TONGUE: UNUSUAL CASE

Nome do Apresentador: Daniele Março de Sousa ROCHA

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Patologia Oral

Resumo: Basaloid squamous cell carcinoma (BSCC) is an aggressive variant of squamous cell carcinoma primarily seen in the upper aerodigestive tract, including the oral cavity, larynx, and esophagus. A 53-year-old Caucasian male complaining of a painful whitish lesion on the base of the right tongue measuring 1.5 cm with an evolution time of 3 months. The patient presented enlarged right submandibular lymph nodes, dysphagia and otalgia. After biopsy, microscopic examination revealed overlying dysplastic epithelium exhibiting cellular and nuclear pleomorphism. Within the connective tissue, the tumor islands and lobules had basaloid cells with hyperchromatic nuclei, scanty cytoplasm and aberrant mitosis. Comedo necrosis was observed in the center of some lobules. The Ki-67 marker, detected by immunohistochemical reaction, was positive in approximately 70% of tumor cells. The final diagnosis of BSCC was obtained. The patient was referred to the oncology center for multidisciplinary treatment.

Autor 1:  Daniele Março de Sousa ROCHA

E-mail 1:  [email protected]

Autor 2:   Karen Corrêa de OLIVEIRA

E-mail 2:  [email protected]

Autor 3 :  Natalia Cristina Trentin BORDIGNON

E-mail 3:  [email protected]

Autor 4:  Manoela Lira REIS

E-mail 4:  [email protected]

Autor 5:  Ricardo Luiz Cavalcanti de ALBUQUERQUE-JÚNIOR

E-mail 5:  [email protected]

Autor 6:  Rogério GONDAK

E-mail 6:  [email protected]