NUMERO: #20240682

Título: DEDIFFERENTIATED LIPOSSARCOMA WITH RHABDOMYOBLASTIC DIFFERENTIATION IN THE MANDIBULAR REGION: A CASE REPORT

Nome do Apresentador: Vitória Campos de GOUVÊA

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Estomatologia

Resumo: Rhabdomyoblastic differentiation is a rare form of presentation of dedifferentiated Liposarcomas. A 35 y.o. patient, smoker, was referred to the oral medicine service with complaints of oral left facial swelling with intraoral ulcers, in the lower left molar region. CT-scanning examination revealed an ill-defined hypodensity measuring 7cm of width in the affected area. Blood pressure examination revealed uncontrolled hypertension of 200/120Hgmm. Preoperatory exams included CBC, INR, BG, VDRL, EBV, HIV. With all preoperative tasks controlled, was performed an incisional biopsy followed by histopathological examination. The suggestive diagnosis of Spindle Cell Sarcoma led to immunohistochemical evaluation, with the following results: CDK4+; MDM2+; Myogenin+; SMA+; SOX10+; CD31+; CD34+; S100 focally +; PanCK-; Ki67 of 20-30%. A final diagnosis compatible with Dedifferentiated Liposarcoma with Rhabdomyoblastic Differentiation led the patient referral to head and neck surgery undergoing a wide margin himi-mandibulectomy and left neck dissection. The patient is under follow up to the date.

Autor 1:  Vitória Campos de GOUVÊA

E-mail 1:  [email protected]

Autor 2:   Dhulle Emily Olegário RIBEIRO

E-mail 2:  [email protected]

Autor 3 :  Fábio Arruda BINDÁ

E-mail 3:  [email protected]

Autor 4:  Tiago Novaes PINHEIRO

E-mail 4:  [email protected]

Autor 5:  Antônio Jorge Araújo de VASCONCELOS II

E-mail 5:  [email protected]

Autor 6:  Lioney Nobre CABRAL

E-mail 6:  [email protected]