NUMERO: #20240657

Título: ORAL MANIFESTATIONS OF PEMPHIGUS VULGARIS DIAGNOSED WITH THE AID OF DIRECT IMMUNOFLUORESCENCE.

Nome do Apresentador: Vitória Parmejane de OLIVEIRA

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Estomatologia

Resumo: A 61-year-old woman was referred to our service with multiple ulcerated lesions in the oral and oropharyngeal mucosa since 6-months, with a satisfactory remission after the onset of corticosteroid treatment. A previous histopathological analysis indicated a suprabasal acantholytic lesion in oropharyngeal lesions. A reduction in corticosteroid therapy was carried out, making it possible to perform a biopsy and immunofluorescence examination. On the day of the biopsy, the patient reported ulcerated lesions on the vaginal mucosa, recurrent epistaxis, and intense oropharyngeal pain. Physical examination revealed painful ulcerated lesions on the gingiva and left buccal mucosa. The immunofluorescence analysis revealed intercellular fluorescent deposits of IgG in the oral epithelium, confirming the diagnosis of pemphigus vulgaris. The patient is being treated with immunosuppressants and is being monitored by our multidisciplinary team.

Autor 1:  Vitória Parmejane de OLIVEIRA

E-mail 1:  [email protected]

Autor 2:   Ana Lívia SANTOS-SOUSA

E-mail 2:  [email protected]

Autor 3 :  Pedro Victor Silva DUARTE

E-mail 3:  [email protected]

Autor 4:  José Cândido Caldeira XAVIER-JÚNIOR

E-mail 4:  [email protected]

Autor 5:  Vitor Bonetti VALENTE

E-mail 5:  [email protected]

Autor 6:  Joely Cristina da Silva TOLEDO

E-mail 6:  [email protected]

Autor 7:  Daniel Galera BERNABÉ

E-mail 7:  [email protected]