Título: aPDT used in the management of osteonecrosis of the jaws: a prospective study
Nome do Apresentador: Fernanda Das Neves LOPES
Categoria do Trabalho: Painel de pesquisa científica (PPC)
Área Temática: Estomatologia
Resumo: Background: There is limitted evidence of Antimicrobial Photodynamic Therapy (aPDT) as a therapeutic modality in the management of osteonecrosis of the jaws. Objective: Our purpose in this pilot study was to evaluate the eficacy of aPDT in patients with osteonecrosis of the jaws. Study design: All patients who had osteonecrosis of the jaws were randomized in two groups: standard group (1), in which irrigation with chlorhexidine 0,12% was weekly performed and antibiotics if necessary; aPDT group (2), in which irrigation with chlorhexidine 0,12% was weekly performed, antibiotics if necessary and weekly aPDT application. The response of osteonecrosis of both groups were considered according to 3 levels: complete healing, partial healing and no response. Results: In group 1, 6 patients underwent surgical treatment and 50% of them had complete healing of osteonecrosis area and 4 patients are waiting for surgery. In group 2, 5 patients underwent also surgical treatment and 80% of them had complete healing, 2 patients no needed surgical intervention and 3 patients are performing aPDT weekly.Conclusion: These preliminary data indicate that aPDT is a promising therapy for osteonecrosis management. However, continuation of this prospective study is necessary to better understanding the aPDT effectiveness in osteonecrosis treatment.
Autor 1: Fernanda Das Neves LOPES
E-mail 1: [email protected]
Autor 2: Joyce Allana Sousa SILVA
E-mail 2: [email protected]
Autor 3 : Laura Luiza Trindade de SOUZA
E-mail 3: [email protected]
Autor 4: André Caroli ROCHA
E-mail 4: [email protected]
Autor 5: Rodrigo Nascimento LOPES
E-mail 5: [email protected]
Autor 6: Alyne Simões GONÇALVES
E-mail 6: [email protected]
Autor 7: Fabio de Abreu ALVES
E-mail 7: [email protected]
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