NUMERO: #20240615

Título: ORAL GRANULOCYTIC SARCOMA AS FIRST SIGN OF ACUTE MYELOID LEUKEMIA: A CASE REPORT

Nome do Apresentador: Liliana Wolf BRAUN

Categoria do Trabalho: Apresentação oral de casos clínicos (AOC)

Área Temática: Oncologia

Resumo: A 79-year-old male presented with asymptomatic gingival swelling that had developed over one month, referred by a dermatologist. The patient's medical history included hypertension, diabetes, treated lung and intestinal cancers, multiple basal cell carcinomas, and peripheral arterial diseases. He was a polypharmacy patient and former smoker. Examination revealed left hemi-maxillary swelling with normochromic color and firm nodules generalized gingiva extending to the hard palate associated with extraoral swelling. In addition, a firm left cervical lymph node was observed. Cranial computed tomography (CT) showed an infiltrative lesion with osteolysis. The leukogram, requested preoperatively for oral biopsy, indicated an increase in the blast count, suggesting a hematological neoplasm. The patient was admitted for investigation, and an incisional biopsy confirmed granulocytic sarcoma. Furthermore, bone marrow biopsy and immunophenotyping revealed acute myeloid leukemia FLT3 positivity. Hematology physicians have proposed chemotherapy combined with radiotherapy. Unfortunately, the patient died four months post-diagnosis.

Autor 1:  Liliana Wolf BRAUN

E-mail 1:  [email protected]

Autor 2:   Luiza Deitos Menti

E-mail 2:  [email protected]

Autor 3 :  Ana Sofia Rabello Fagherazzi

E-mail 3:  [email protected]

Autor 4:  Luis Afonso Tochetto

E-mail 4:  [email protected]

Autor 5:  Marco Antônio Trevizani Martins

E-mail 5:  [email protected]

Autor 6:  Vinicius Coelho Carrard

E-mail 6:  [email protected]

Autor 7:  Manoela Domingues Martins

E-mail 7:  [email protected]