NUMERO: #20240026

Título: THE USE OF UBIQUINONE TO IMPROVE THE HEALING OF SOFT AND HARD MAXILLARY TISSUES - A SYSTEMATIC REVIEW

Nome do Apresentador: Alini Cardoso SOARES

Categoria do Trabalho: Painel de Revisões narrativas ou sistemáticas (PRN)

Área Temática: Patologia Oral

Resumo: Objective: To survey the scientific literature for conclusive evidence about the capacity of ubiquinone to improve the healing process of soft and hard maxillary tissue.

Study Design: A systematic review was conducted according to the PRISMA 2020 statement. An electronic search was undertaken in six databases and in the gray literature.

Results: Eight studies were identified, four of them in vitro, three in vivo, and one clinical. All articles demonstrated that ubiquinone accelerates the repair of soft tissue, whereas one study found little effect on the remodeling of bone tissue. Despite the possibility that ubiquinone application may be beneficial, the limited knowledge about the action of this coenzyme on oral tissue repair requires further preclinical studies before the development of human clinical trials.

Conclusion: This systematic review provides valuable information about potential new medications that could help the healing of oral tissues, especially for oral and maxillofacial surgeons.

Autor 1:  Alini Cardoso SOARES

E-mail 1:  [email protected]

Autor 2:   Camila Barcellos CALDERIPE

E-mail 2:  [email protected]

Autor 3 :  Rafael dos Santos GIORGIS

E-mail 3:  [email protected]

Autor 4:  Luisa Quevedo GRAVE

E-mail 4:  [email protected]

Autor 5:  Lauren Frenzel SCHUCH

E-mail 5:  [email protected]

Autor 6:  Ana Carolina Uchoa VASCONCELOS

E-mail 6:  [email protected]