NUMERO: #20230664

Título: LANGERHANS CELL HISTIOCYTOSIS ASSOCIATED WITH ERDHEIN-CHESTER´S DISEASE: A RARE OCCURRENCE IN THE SAME PATIENT

Nome do Apresentador: Paulo de Camargo MORAES

Categoria do Trabalho: Apresentação oral de casos clínicos (AOC)

Área Temática: Estomatologia

Resumo: Histiocytosis, Rosai-Dorfman and Erdhein-Chester are rare diseases caused by infiltration of histiocytes that can involve one or multiple organs. Diagnosis is made based on imaging and biopsy of the lesions. The immunohistochemistry profile in Langerhans cell histiocytosis includes positivity to S-100 and CD1-A whereas in Erdhein-Chester disease, lesions are positive to CD68 and negative to S-100 and CD1-A. A 60-year-old black female, whose main complaint was teeth loss, reported recent dental implant placement and retroperitoneal fibrosis treated with mycophenolate mofetil. On intraoral examination she had tooth mobility, ulcerated lesions, and alveolar bone loss. An incisional biopsy was performed for which the diagnosis was Langerhans cell histiocytosis proven positive to S-100 and CD1-A. Due to the report of retroperitoneal fibrosis, the patient was referred to hematology, which confirmed the association between Langerhans cell histiocytosis and Erdhein - Chester This case has been under observation for two and a half years.

Autor 1:  Paulo de Camargo MORAES

E-mail 1:  [email protected]

Autor 2:   Daniela prata TACCHELLI

E-mail 2:  [email protected]

Autor 3 :  Victor a m MONTALLI

E-mail 3:  [email protected]

Autor 4:  Bruno felipe GAIA

E-mail 4:  [email protected]

Autor 5:  Thaís bianca BRANDÃO

E-mail 5:  thais.brandã[email protected]

Autor 6:  Ariadne padilha de ANDRADE

E-mail 6:  [email protected]

Autor 7:  Marcelo SPERANDIO

E-mail 7:  [email protected]