NUMERO: #20230246

Título: REPORT OF A NEW CASE OF CONTROVERSIAL GRANULAR CELL ODONTOGENIC FIBROMA

Nome do Apresentador: Raisa Jordana Geraldine SEVERINO LAZO

Categoria do Trabalho: Apresentação oral de casos clínicos (AOC)

Área Temática: Patologia Oral

Resumo: Granular cell odontogenic fibroma (GCOF) is a controversial benign neoplasm of uncertain histogenesis. A 35-year-old female patient was referred to the Hospital for painless posterior mandible swelling. Panoramic radiography and CT showed a multilocular septal lesion with defined borders with expansion of the buccal and lingual cortex. A biopsy was performed and subsequently the lesion was surgically enucleated. Histopathologically, cellular connective tissue, fibroblastic, with presence of islands and filaments of odontogenic epithelium of inactive aspect, associated with dentinoid-like calcifications, large granular mesenchymal cells with eccentric nuclei and eosinophilic granular cytoplasm were observed. Immunohistochemical staining with different markers such as CD68, vimentin, AE1/AE3, CK14, S-100, and EMA confirmed the diagnosis of GCOF. Subsequently, the patient underwent surgery to fill the bone defect. A 39-month follow-up revealed no signs of tumor recurrence. The area showed complete healing, and the patient is ready for the rehabilitation phase with dental implants.

Autor 1:  Raisa Jordana Geraldine SEVERINO LAZO

E-mail 1:  [email protected]

Autor 2:   Allan Vinícius MARTINS-DE-BARROS

E-mail 2:  [email protected]

Autor 3 :  Jéssica DA SILVA CUNHA

E-mail 3:  [email protected]

Autor 4:  Rómulo Augusto DE PAIVA MACEDO

E-mail 4:  [email protected]

Autor 5:  Mohammed N. ISLAM

E-mail 5:  [email protected]

Autor 6:  Belmiro Cavalcanti DO EGITO VASCONCELOS

E-mail 6:  [email protected]

Autor 7:  Marianne de Vasconcelos CARVALHO

E-mail 7:  [email protected]