NUMERO: #20230105

Título: LOWE SYNDROME: FIRST REPORT OF MULTIPLE ODONTOGENIC KERATOCYSTS

Nome do Apresentador: Ricardo Martinez PEDRAZA

Categoria do Trabalho: Apresentação oral de casos clínicos (AOC)

Área Temática: Estomatologia

Resumo: Lowe syndrome (LS; OMIM #309000), also known as oculocerebrorenal syndrome is a rare (1:500,000) genetic disorder inherited in an X-linked manner. LS is characterized by alterations in the nervous system, kidneys, eyes. A Mexican 25-year-old male patient presented for diagnosis of multiple radiolucent lesions observed on panoramic radiography. Clinically, cognitive delay, eye disorders and kidney involvement were the key findings to support the diagnosis of LS. Three well-delimited radiolucent lesions were observed in the right and left mandibular angle and symphysis. Incisional biopsy and decompression were performed under general anesthesia. Histological examination revealed the diagnosis of odontogenic keratocyst (OKC) for all lesions. The lesions in the right and left mandibular angles have completely decompressed, while the symphyseal lesion was enucleated. A 2-month follow-up shows the bone healing process. Oral manifestations in patients with LS are rarely reported. Furthermore, this is the first report of multiple OKC affecting patients with LS.

Autor 1:  Ricardo Martinez PEDRAZA

E-mail 1:  [email protected]

Autor 2:   Hélen Kaline Farias BEZERRA

E-mail 2:  [email protected]

Autor 3 :  Liliana Curiel MAGAÑA

E-mail 3:  [email protected]

Autor 4:  Laura Carolina Pinzón MONTAÑA

E-mail 4:  [email protected]

Autor 5:  Yenifer Rodríguez LINO

E-mail 5:  [email protected]

Autor 6:  Ana Gabriela Hernández S

E-mail 6:  [email protected]

Autor 7:  Hercílio MARTELLI-JÚNIOR

E-mail 7:  [email protected]