NUMERO: #20230102

Título: ORAL CANCER IN A PATIENT WITH FANCONI ANEMIA, 28 YEARS AFTER HEMATOPOIETIC STEM CELL TRANSPLANTATION: CASE REPORT

Nome do Apresentador: Joana Leticia VENDRUSCOLO

Categoria do Trabalho: Apresentação oral de casos clínicos (AOC)

Área Temática: Estomatologia

Resumo: Patients with Fanconi Anemia (FA) have a higher risk of developing oral cancer, particularly after hematopoietic stem cell transplantation (HSCT). In this paper, we describe a 42-year-old female patient who underwent allogeneic HSCT from a sibling donor in 1995 and has been monitored by the same dental team for more than ten years. She received an anatomopathological exam this year following incisional biopsies, which revealed moderately differentiated squamous cell carcinoma on the tongue dorsum and a moderately dysplastic region on the lingual border. She was recommended to the medical staff for tumor therapy after the dysplasic area was removed with a high-power laser. A specialized dental staff must constantly examine patients with AF because HSCT conditioning therapies, such as chemotherapy and/or radiotherapy, can play a significant role in malignant transformation and this risk grows over time.

Autor 1:  Joana Leticia VENDRUSCOLO

E-mail 1:  [email protected]

Autor 2:   Waleska Tychanowicz KOLODZIEJWSKI

E-mail 2:  [email protected]

Autor 3 :  Cassius Carvalho TORRES-PEREIRA

E-mail 3:  [email protected]