NUMERO: #20220242

Título: ADENOID CYSTIC CARCINOMA OF MINOR SALIVARY GLANDS: A 10-YEAR SINGLE-CENTER RETROSPECTIVE STUDY

Nome do Apresentador: Daniella ESTANHO de Lima Flavio

Categoria do Trabalho: Trabalhos Aprovados para Disponibilização em Vídeo (ADV)

Área Temática: Patologia Oral

Resumo: Objective: The aim of this study was to evaluate the clinicopathologic features of adenoid cystic carcinoma of minor salivary glands (ACC-MSG) from a single Brazilian Oral Pathology Laboratory. Study design: Clinical data and conventionally stained slides of all cases diagnosed as ACC-MSG between 2012 and 2021 were retrieved from the Laboratory files and microscopically reviewed. Results: There were 23 cases of ACC-MSG in the last 10 years (2.3 cases/year) affecting 16 women (69.6%) and 7 men (30.4%) (mean age of 53 years). The palate was the most affected site (10 cases, 43.5%), followed by the floor of mouth (5 cases, 21.7%), buccal mucosa (3 cases, 13%), and tongue (3 cases, 13%). The main clinical presentation was of a nodule (16 cases; 69.6%), 4 of them displaying an ulcerated surface. Four cases appeared as ulcers (17.4%). Pain was reported in 12 cases (52.2%). Microscopically, 12 cases (52.2%) showed both cribriform and tubular patterns, while focal solid areas were observed in 14 cases (60.9%). Ten cases (43.5%) exhibited perineural invasion and a single case showed necrosis. Conclusion: The clinicopathologic profile of ACC-MSG in this Brazilian population is similar to previous studies. Approximately half of cases exhibited pain and perineural invasion.

Autor 1:  Daniella ESTANHO de Lima Flavio

E-mail 1:  [email protected]

Autor 2:   Thamyres Campos Fonsêca

E-mail 2:  [email protected]

Autor 3 :  Claudia Maria Pereira

E-mail 3:  [email protected]

Autor 4:  Juliana de Noronha Santos Netto

E-mail 4:  [email protected]

Autor 5:  Michelle Agostini

E-mail 5:  [email protected]

Autor 6:  Mário José Romañach

E-mail 6:  [email protected]

Autor 7:  Aline Correa Abrahão

E-mail 7:  [email protected]