NUMERO: #20220230

Título: ORAL DIAGNOSIS OF PLASMABLASTIC LYMPHOMA - REPORT OF TWO CASES

Nome do Apresentador: Joana Letícia SCHORR

Categoria do Trabalho: Trabalhos Aprovados para Disponibilização em Vídeo (ADV)

Área Temática: Estomatologia

Resumo: Plasmablastic lymphoma (PBL) is a rare and aggressive B-cell malignancy that usually has a poor prognosis. Oral manifestations in the PBL are second in frequency most commonly location is palate or gingiva. Here, we report 2 cases of PBL with palate manifestation. One man, 51-year-old, HIV negative presenting with an asymptomatic lesion and a female, HIV positive and smoker showing a symptomatic growth. Clinically, both lesions exhibited a nodule with ulcerated surface, undefined limits, purplish color. An incisional biopsy was performed, with a histopathological diagnosis compatible with plasma cell neoplasm. Immunohistochemical analysis confirmed the diagnosis. They were referred to hematoncology team for treatment which consisted in DA-EPOCH (dose adjusted etoposide, prednisolone, vincristine, cyclophosphamide and doxorubicin) combined with MADIT (combination of methotrexate, cytosine arabinoside, and dexamethasone intrathecal). The male patient is receiving the chemotherapy and the female patient died during the 3rd cycle of chemotherapy of COVID-19.

Autor 1:  Joana Letícia SCHORR

E-mail 1:  [email protected]

Autor 2:   UARLEI NOGUEIRA PORTO

E-mail 2:  [email protected]

Autor 3 :  TUANY RAFAELI SCHMIDT

E-mail 3:  [email protected]

Autor 4:  GRAZIELLE OLIVEIRA STELTER

E-mail 4:  [email protected]

Autor 5:  MARCO ANTONIO TREVIZANI MARTINS

E-mail 5:  [email protected]

Autor 6:  VINÍCIUS COELHO CARRARD

E-mail 6:  [email protected]

Autor 7:  MANOELA DOMINGUES MARTINS

E-mail 7:  [email protected]