NUMERO: #20220199

Título: ORAL MUCOSITIS IN PATIENTS TREATED WITH METHOTREXATE SUBMITTED TO PROPHYLACTIC PHOTOBIOMODULATION IN AN ONCOLOGY SERVICE

Nome do Apresentador: Raylane Farias de ALBUQUERQUE

Categoria do Trabalho: Trabalhos Aprovados para Disponibilização em Vídeo (ADV)

Área Temática: Oncologia

Resumo: Objective: To evaluate the incidence of oral mucositis (OM) in patients treated with methotrexate (MTX) undergoing prophylactic photobiomodulation in the oral cavity in a pediatric oncology service. Study design: A cross-sectional study was performed with 14 patients who underwent 52 chemotherapy sessions in total. Photobiomodulation and clinical examination of the oral cavity were performed daily from the first day of chemotherapy until hospital discharge. When present, OM was classified according to the National Cancer Institute table. Results: During hospitalizations for MTX, OM was present in 23% of cases, with Grade 1 responsible for 10% and Grade 2 for 13%. On the other hand, OM after hospital discharge was present in 11% of the cases, being manifested only in Grade 2. Among the other signs and symptoms found were odynophagia, dysphagia and pseudomembranous candidiasis. The average dose of MTX performed during hospitalization was 18,750mg. Each patient performed an average of 3 photobiomodulation sessions per hospitalization. The median time to develop mucositis after hospital discharge was 3 days. Conclusion: prophylactic photobiomodulation was associated with a low incidence of OM and no cases of severe OM in patients undergoing high-dose MTX.

Autor 1:  Raylane Farias de ALBUQUERQUE

E-mail 1:  [email protected]

Autor 2:   Maria Fernanda LIMEIRA Feitosa

E-mail 2:  [email protected]

Autor 3 :  Nayara Gabriela Silva PENA

E-mail 3:  [email protected]

Autor 4:  Virgínia Andrade de SOUZA

E-mail 4: 

Autor 5:  Gustavo Pina GODOY

E-mail 5:  [email protected]

Autor 6:  Lucas Nascimento RIBEIRO

E-mail 6:  [email protected]

Autor 7:  Igor Henrique Morais SILVA

E-mail 7:  [email protected]