NUMERO: #20220131

Título: PROFILE OF ORAL MANIFESTATIONS OF GRAFT VERSUS HOST DISEASE

Nome do Apresentador: Juliana l SCHUSSEL

Categoria do Trabalho: Trabalhos Aprovados para Disponibilização em Vídeo (ADV)

Área Temática: Odontologia hospitalar

Resumo: Hematopoietic stem cell transplantation (HSCT) is indicated for the treatment of several types of hematological diseases. A post-HSCT complication of concern is the development of graft-versus-host disease (GVHD). Clinically, oral GVHD is characterized by painful, hyperkeratotic, erythematous, ulcerative, atrophic inflammatory lesions and presents an increased risk of developing a second neoplasm, such as squamous cell carcinoma. Objective: To identify the profile of the oral manifestations of GVHD, favoring early diagnosis to determine the most appropriate treatment for the severity of the disease. Study Design: We performed a retrospective analysis of oral GVHD images in patients´ post-HSCT and clinical information. Results: The retrospective evaluation of medical records showed an important variation of lesions, the most cited being lichenoid lesions, erythema, and hyperkeratotic plaques, as well as their locations, frequencies, and symptoms. Conclusion: It is evident that GVHD manifests itself in different ways in oral cavity, therefore, knowing its possible clinical presentation well and knowing how to classify it in terms of severity becomes important not only for determining the most appropriate prognosis and treatment, as well as to differentiate it from lesions with malignant potential.

Autor 1:  Juliana l SCHUSSEL

E-mail 1:  [email protected]

Autor 2:   Julia Rahal de CAMARGO

E-mail 2:  [email protected]

Autor 3 :  Rafael Zancan MOBILE

E-mail 3:  [email protected]

Autor 4:  Stephanie Warnavin

E-mail 4:  [email protected]

Autor 5:  Cassius Carvalho TORRES-PEREIRA

E-mail 5:  [email protected]