NUMERO: #20220115

Título: AFATINIB-RELATED ORAL ULCERATION

Nome do Apresentador: Luiza Rodrigues HELLMEISTER

Categoria do Trabalho: Trabalhos Aprovados para Disponibilização em Vídeo (ADV)

Área Temática: Estomatologia

Resumo: Treatment of malignant neoplasms with antibodies is associated with oral mucosal side-effects. Afitinib may cause mucocutaneous lesions that mimic ordinary oral ulceration due to blockage of epidermal growth factor. The purpose of this report is to describe a case of mucocutanous lesions associated with Afatinib. A 63-year-old Caucasian female diagnosed with non-small cell lung carcinoma presented with painful recurrent oral ulcerations since starting treatment for her lung disease. On intraoral examination, irregular 3 to 6-mm ulcers surrounded by an erythematous halo were detected in her lower labial mucosa, hard palate and lingual frenulum. On extra-oral examination, ulcerative lesions were also detected on both right and left aspects of her hallux (big toe) nail. The patient was treated with low-level laser therapy with marked clinical and symptomatic improvement.

Autor 1:  Luiza Rodrigues HELLMEISTER

E-mail 1:  [email protected]

Autor 2:   Larissa Araujo AGATTI

E-mail 2:  [email protected]

Autor 3 :  Andrea MENEGUETTI

E-mail 3:  [email protected]

Autor 4:  Aguinaldo Silva GARCEZ

E-mail 4:  [email protected]

Autor 5:  Victor Angelo Martins MONTALLI

E-mail 5:  [email protected]

Autor 6:  Paulo de Camargo MORAES

E-mail 6:  [email protected]

Autor 7:  Marcelo SPERANDIO

E-mail 7:  [email protected]