NUMERO: #20220080

Título: PLASMACYTOMA AND PLASMA CELL MYELOMA AFFECTING THE JAWS: A MULTI-INSTITUTIONAL COLLABORATIVE STUDY.

Nome do Apresentador: Lucas Lacerda de SOUZA

Categoria do Trabalho: Apresentação Oral de Séries de Casos Clínicos (AOS)

Área Temática: Patologia Oral

Resumo: Plasma cell neoplasms represent the proliferation of single clone of plasma cells with production of monoclonal immunoglobulins. This study aims to report a case series of plasmacytoma (PMC) and multiple myeloma (MM) of the oral cavity. Data were retrospectively retrieved and clinical, radiographic, microscopic, immunohistochemistry and follow-up status were collected. Fifty-two cases were included (28 PMC and 24 MM) with a mean age of 59.4 years (range 27-88) and no sex predilection. Lesions were mostly presented as painful swellings in the mandible. Radiographic aspects evidenced multilocular poorly defined lesions and microscopic examinations showed proliferation of plasma cells with abundant eosinophilic cytoplasm. Immunohistochemistry was positive for plasma cell markers and negative for CD20 and CD3, with kappa light chain monoclonality predominance. Overall survival was poor and after 5 years 26.6% of patients were alive. PMC and MM are aggressive neoplasms with poor prognosis for the affected patients.

Autor 1:  Lucas Lacerda de SOUZA

E-mail 1:  [email protected]

Autor 2:   Pablo Agustin VARGAS

E-mail 2:  [email protected]

Autor 3 :  Bruno Augusto Benevenuto DE ANDRADE

E-mail 3:  [email protected]

Autor 4:  Fabio Ramôa PIRES

E-mail 4:  [email protected]

Autor 5:  Ciro Dantas SOARES

E-mail 5:  [email protected]

Autor 6:  Hélder Antônio Rebelo PONTES

E-mail 6:  [email protected]

Autor 7:  Oslei Paes DE ALMEIDA

E-mail 7:  [email protected]