NUMERO: #20220024

Título: SERIES OF 62 CASES OF ACINIC CELL CARCINOMA IN THE ORAL AND MAXILLOFACIAL REGION

Nome do Apresentador: Laura Borges KIRSCHNICK

Categoria do Trabalho: Trabalhos Aprovados para Disponibilização em Vídeo (ADV)

Área Temática: Patologia Oral

Resumo: Objective: The aim of the study was to integrate the clinicopathological and prognostic features of acinic cell carcinoma (AciCC) of oral and maxillofacial region.
Study Design: The study was approved by the Ethics Committee of the Universidade Estadual de Campinas (No. 43463521.1.0000.5418). AciCC cases were retrospectively retrieved from 7 pathology centers of three different countries.
Results: From a total of 62 cases, females (69.35%) were more affected with a mean age of 45.96 years old. The parotid gland (79.03%) was more involved with an asymptomatic (61.90%) nodule (52.63%). AciCC has four main histopathological patterns - solid, papillary-cystic, microcystic and follicular -, but the association of two patterns was the most common feature (51.28%), with a conventional histological grade (86.66%). Surgical resection (60.00%) was the main treatment choice, only three cases recurred and six reported some metastatic lesion. The mean follow-up time was 63.05 months and 2 patients died because of the disease.
Conclusion: Although, AciCC lesions have an indolent course in the majority of cases, high histopathological transformation, presence of nodal metastasis and recurrence were prognostic factors for AciCC of the oral and maxillofacial region.

Autor 1:  Laura Borges KIRSCHNICK

E-mail 1:  [email protected]

Autor 2:   Jean Nunes dos SANTOS

E-mail 2:  [email protected]

Autor 3 :  Elismauro Francisco de MENDONÇA

E-mail 3:  [email protected]

Autor 4:  Willie van HEERDEN

E-mail 4:  [email protected]

Autor 5:  Elena Maria José Román TAGER

E-mail 5:  [email protected]

Autor 6:  Pablo Agustin VARGAS

E-mail 6:  [email protected]

Autor 7:  Manoela Domingues MARTINS

E-mail 7:  [email protected]