NUMERO: #20220004

Título: A SYSTEMATIC REVIEW OF THE DIRECT COSTS ASSOCIATED WITH THE MANAGEMENT OF MUCOSITIS

Nome do Apresentador: Leticia RODRIGUES-OLIVEIRA

Categoria do Trabalho: Apresentação Oral de Pôster de Revisões Narrativas ou sistemáticas (PRN)

Área Temática: Oncologia

Resumo: Objective: To evaluate and report the direct economic outcomes associated with the management of mucositis across several cancer treatments through a systematic review. Study Design: A systematic search using the databases Scopus, MEDLINE/PubMed, and Embase to identify articles that provided data on costs associated with mucositis in cancer patients following antineoplastic therapies. Results: 37 studies were included. The costs attributable to mucositis ranged from 1,124.47 to 29,9214.14 US dollars (USD) per patient in the hematopoietic stem cell transplantation setting; from 51.23 to 33,560.58 USD per patient in the radiotherapy/ chemoradiotherapy/radiotherapy plus molecular targeted therapy setting; from 4.18 to 31,963.64 USD per patient in the chemotherapy setting; from 565.85 to 20,279.12 USD per patient when cancer treatment was not specified; from 12.42 to 5,670.46 USD per patient for the multimodal therapy setting; and from 45.78 to 3,484.91 USD per patient in the molecular targeted therapy setting. Conclusion: Mucositis is associated with increased resource use, consultations, hospitalizations and extended hospitalizations, leading to a substantial incremental cost that exacerbates the economic burden on the patient, health plan and health system across several cancer treatments and diagnosis. More studies with a prospective evaluation of the economic costs associated with mucositis management are needed.

Autor 1:  Leticia RODRIGUES-OLIVEIRA

E-mail 1:  [email protected]

Autor 2:   Manoela Domingues MARTINS

E-mail 2:  [email protected]

Autor 3 :  Cesar Augusto MIGLIORATI

E-mail 3:  [email protected]

Autor 4:  Gustavo Nader MARTA

E-mail 4:  [email protected]

Autor 5:  Thaís Bianca BRANDÃO

E-mail 5:  [email protected]

Autor 6:  Alan Roger SANTOS-SILVA

E-mail 6:  [email protected]

Autor 7:  Ana Carolina PRADO-RIBEIRO

E-mail 7:  [email protected]