NUMERO: #20260563

Título: Polymorphous adenocarcinoma of the hard palate: a diagnostic challenge in oral pathology

Nome do Apresentador: Daniel A. DROGUETT Ossa

Categoria do Trabalho: Pôster - Relato de Caso ou Série de Casos

Área Temática: Patologia Oral

Resumo: A 67-year-old female presented with a slowly enlarging, asymptomatic palatal mass of approximately one year of evolution, causing functional discomfort during speech. Clinical examination revealed a lobulated, non-ulcerated lesion of the right hard palate measuring approximately 4 cm. Initial incisional biopsy demonstrated a low-grade monomorphic tubular neoplasm, raising differential diagnoses including pleomorphic adenoma and adenoid cystic carcinoma.
The patient underwent surgical excision. Histopathological evaluation of the resection specimen confirmed a polymorphous adenocarcinoma of minor salivary gland origin, with tubular architecture, low proliferative index (Ki-67 ~25%), and positive immunoexpression for CK7 and p63. The deep surgical margin was involved.
This case illustrates a low-grade malignant neoplasm clinically and histologically mimicking a benign tumor, highlighting the diagnostic challenge and the importance of thorough clinicopathological correlation. Adjuvant radiotherapy was indicated.

Autor 1:  Daniel A. DROGUETT Ossa

E-mail 1:  [email protected]

Autor 2:   Erik M. MORALES Mejias

E-mail 2:  [email protected]

Autor 3 :  Cristian M. GUERRERO Barahona

E-mail 3:  [email protected]

Autor 4:  Marcelo R. SÁNCHEZ Peña

E-mail 4:  [email protected]

Autor 5:  Glomaryeth C. LUQUE Sulbaran

E-mail 5:  [email protected]

Autor 6:  Bernardo A. VENEGAS Rojas

E-mail 6:  [email protected]