NUMERO: #20260556

Título: SINONASAL TRACT ANGIOFIBROMA: A SYSTEMATIC REVIEW

Nome do Apresentador: Jéssica da Silva CUNHA

Categoria do Trabalho: Pôster - Investigação Original (IO)

Área Temática: Patologia Oral

Resumo: Objective: To synthesize the clinical, imaging, and treatment characteristics of sinonasal tract angiofibroma reported in the last decade. Study design: A systematic review conducted according to PRISMA guidelines and registered in PROSPERO. A comprehensive search was performed in MEDLINE, Embase, Web of Science, Scopus, and LILACS (2015-2025). Observational studies reporting individual patient data were included. Results: Twenty-five studies comprising 25 cases were included. Most patients were male (92%), with a mean age of 31.2 years. The most frequent symptoms were epistaxis (72%) and nasal obstruction (52%). Tumors originated predominantly in the posterior nasal cavity/nasopharynx, with extension to deep facial spaces (60%), paranasal sinuses (48%), and the skull base (44%). Treatment was divided into endoscopic and open surgical approaches, with endoscopic resection and surgical excision being the most common (28% each). Residual tumor was identified in 12% of cases, while recurrence occurred in 16%. Follow-up was ≤1 year in 48% of cases. Immunohistochemical analysis showed limited β-catenin positivity (16%), with one case also positive for AR. Conclusion Sinonasal tract angiofibroma is a rare, locally aggressive entity with variable clinical presentation, underscoring the need for further studies to enhance diagnostic accuracy and guide therapeutic decision-making.

Autor 1:  Jéssica da Silva CUNHA

E-mail 1:  [email protected]

Autor 2:   Letícia Francine Silva RAMOS

E-mail 2:  [email protected]

Autor 3 :  Gabrielle Vieira dos SANTOS

E-mail 3:  [email protected]

Autor 4:  Guilherme Rodrigues Wanderley de OLIVEIRA

E-mail 4:  [email protected]

Autor 5:  Stefânia Jeronimo FERREIRA

E-mail 5:  [email protected]

Autor 6:  Fábio Andrey da Costa ARAÚJO

E-mail 6:  [email protected]

Autor 7:  Marianne de Vasconcelos CARVALHO

E-mail 7:  [email protected]