NUMERO: #20260389

Título: ORAL AND BUCAL MANIFESTATIONS OF PATIENTS DIAGNOSED WITH MUSCULAR DYSTROPHIES: A SYSTEMATIC REVIEW AND META-ANALYSIS

Nome do Apresentador: Christiane Caminiti CHIARADIA

Categoria do Trabalho: Pôster - Investigação Original (IO)

Área Temática: Odontologia para pacientes especiais

Resumo: Objective: This study aims to answer the question: what are the oral and dental manifestations of patients diagnosed with muscular dystrophies? Study design: Prisma Checklist guidelines was followed and JBI Institute checklists for risk of bias were used (prevalence and cross-sectional studies). Electronic searches on five databases and grey literature were performed up to April 2024 and identified 4413 studies. After applying the elegibility criteria, reading the texts in full, 17 studies remained. Results: The total sample was 882 participants, aging between 3 and 64 years old, the majority were male. Three types of muscular dystrophies were described: Duchenne muscular dystrophy (DMD), Myotonic dystrophy, and Facioscapulohumeral dystrophy. A quantitative synthesis was performed only for DMD and 3 features: open bite, macroglossia and posterior crossbite. The pooled prevalence of open bite was approximately 38% (95% CI: 29-47%). The pooled prevalence of macroglossia was approximately 40% (95% CI: 21-62%). The pooled prevalence of posterior crossbite was approximately 57% (95% CI: 41-72%). Conclusion: Quantitative synthesis was only feasible for Duchenne muscular dystrophy, demonstrating a high prevalence of open bite, macroglossia, and posterior crossbite. However, given that most included studies presented moderate to high risk of bias, these findings should be interpreted with caution.

Autor 1:  Christiane Caminiti CHIARADIA

E-mail 1:  [email protected]

Autor 2:   Janaina Braga MEDINA

E-mail 2:  [email protected]

Autor 3 :  Bruna de Oliveira RECH

E-mail 3:  [email protected]

Autor 4:  Nathália Abdala ARAÚJO

E-mail 4:  [email protected]

Autor 5:  Marcos Altyeres Coelho VASCONCELOS

E-mail 5:  [email protected]

Autor 6:  Nicole Chouzende SILVA

E-mail 6:  [email protected]

Autor 7:  Karem López ORTEGA

E-mail 7:  [email protected]