NUMERO: #20260382

Título: SEVERE ADVERSE REACTION TO MMRV VACCINE WITH ORAL MUCOSAL INVOLVEMENT: CASE REPORT AND LITERATURE REVIEW

Nome do Apresentador: Marília Ferreira ANDRADE

Categoria do Trabalho: Pôster - Relato de Caso ou Série de Casos

Área Temática: Odontologia hospitalar

Resumo: The measles-mumps-rubella-varicella (MMRV) vaccine is widely regarded as safe; however, rare severe adverse reactions, including anaphylaxis, encephalitis, Stevens-Johnson syndrome (SJS), erythema multiforme, thrombocytopenia, pneumonia, and disseminated varicella-like infection, have been reported. Oral mucosal involvement, as seen in SJS and erythema multiforme, manifests as painful ulcerations, hemorrhagic crusting, and extensive epithelial sloughing. This study presents a literature review and case report of a 16-month-old boy who developed a severe vaccine-associated reaction. Initial symptoms included a 10-day fever and gingival hemorrhage, progressing to widespread ulcerative and erosive lesions across the oral mucosa, accompanied by pneumonia. The patient required 23 days of hospitalization and extensive diagnostic workup before a diagnosis of MMRV vaccine reaction linked to the varicella component was confirmed. This case underscores the need for prompt recognition of severe mucocutaneous reactions post-immunization in pediatric dentistry.

Autor 1:  Marília Ferreira ANDRADE

E-mail 1:  [email protected]

Autor 2:   Maria Eduarda Medeiros MACEDO

E-mail 2:  [email protected]

Autor 3 :  Arthur Lacerda MENDONÇA

E-mail 3:  [email protected]

Autor 4:  Alan Bartasson Ferreira ROSA

E-mail 4:  [email protected]

Autor 5:  Frederico Chaves SALOMÃO

E-mail 5:  [email protected]

Autor 6:  Juliana Mota SIQUEIRA

E-mail 6:  [email protected]

Autor 7:  Kelen Christine do Nascimento SOUZA

E-mail 7:  [email protected]