NUMERO: #20260205

Título: DIAGNOSTIC CHALLENGE OF A PIGMENTED PALATAL LESION: A CASE REPORT

Nome do Apresentador: Blanca Esmeralda Vázquez Báez

Categoria do Trabalho: Pôster - Relato de Caso ou Série de Casos

Área Temática: Patologia Oral

Resumo: Oral pigmented lesions include melanocytic nevi, melanoacanthoma, and melanoma, a malignant neoplasm with poor prognosis that may mimic other lesions, making histopathologic diagnosis through biopsy essential.
A specimen was received from a 43-year-old female patient presenting with a macule on the palate, showing black and brown coloration. An initial diagnosis of melanoacanthoma was made, however, subsequent enlargement prompted biopsy.
Histopathologic examination revealed a pigmented neoplasm involving the basal layer, with cellular pleomorphism, nuclear hyperchromatism and subepithelial melanin deposition. Immunohistochemistry was positive for Melan-A, Ki-67, S-100, SOX10 and HMB-45, supporting a final diagnosis of oral melanoma.
Timely biopsy of oral pigmented lesions aims to rule out malignancy. Adequate deep incisional sampling from the area with the most significant clinical changes, allows for better evaluation. Suboptimal samples may compromise diagnosis, while adjunctive techniques increase diagnostic accuracy. The patient was referred to oncology.

Autor 1:  Blanca Esmeralda Vázquez Báez

E-mail 1:  [email protected]

Autor 2:   Héctor Esquivias Lozano

E-mail 2: 

Autor 3 :  Ulises Vázquez Zúñiga

E-mail 3:  [email protected]

Autor 4:  Alberto Flores Longoria

E-mail 4:  [email protected]

Autor 5:  José David Ramos Baena

E-mail 5:  [email protected]

Autor 6:  Karla Mayela Avelar Juárez

E-mail 6:  [email protected]