NUMERO: #20260138

Título: Active Oxygen Gel Combined With Surgical Management Of Medication-Related Osteonecrosis Of The Jaw: A Case Report

Nome do Apresentador: Alan Alves MACHADO

Categoria do Trabalho: Pôster - Relato de Caso ou Série de Casos

Área Temática: Cirurgia e traumatologia bucomaxilofacial

Resumo: To report a case of recurrent Medication-related Osteonecrosis of the Jaw (MRONJ) managed with surgical intervention combined with an active oxygen gel as an adjunct to wound healing. A 77-year-old female with a history of breast cancer and bone metastasis, previously treated with bisphosphonates, presented with stage 2 MRONJ following facial trauma. Intraoral examination revealed bone exposure in the right maxillary alveolar ridge and tooth mobility on the left side. Surgical debridement with Platelet-Rich Fibrin (L-PRF) was performed, followed by extraction of tooth 23. Subsequently, a new stage 2 MRONJ lesion developed on the left side and was treated with surgery associated with topical oxygen gel (blue®m). After three surgical procedures, no clinical signs of infection were observed, and complete mucosal healing was achieved. The combined approach was associated with favorable clinical outcomes, suggesting a potential adjunctive role of oxygen-based gels in the management of recurrent MRONJ cases in practice.

Autor 1:  Alan Alves MACHADO

E-mail 1:  [email protected]

Autor 2:   Thalles Yurgen Balduino

E-mail 2:  [email protected]

Autor 3 :  Riéli Elis Schulz

E-mail 3:  [email protected]

Autor 4:  Ariadne Cristiane Cabral da Cruz

E-mail 4:  [email protected]

Autor 5:  Cesar Augusto Magalhães Benfatti

E-mail 5:  [email protected]

Autor 6:  Anna Torrezani

E-mail 6:  [email protected]