NUMERO: #20260056

Título: Clinical and Epidemiological Profile of Oral Fungal and Bacterial Infections: A 20-Year Retrospective Study

Nome do Apresentador: Luís Henrique CARDOSO

Categoria do Trabalho: Pôster - Investigação Original (IO)

Área Temática: Patologia Oral

Resumo: Objective: To analyze the clinical and epidemiological profile of major fungal and bacterial infections with oral manifestations diagnosed in a reference oral pathology laboratory in Vale do Paraíba over 20 years.
Study design: Retrospective analysis of histopathological reports of candidiasis, paracoccidioidomycosis, histoplasmosis, syphilis, tuberculosis, and actinomycosis, confirmed by slide review, with collection of demographic, clinical, and morphological data.
Results: Candidiasis was the most frequent infection (n=87; 1.1%), followed by paracoccidioidomycosis (n=19; 0.2%) and actinomycosis (n=18; 0.2%). Syphilis (n=5; 0.1%), tuberculosis (n=1; 0.01%), and histoplasmosis (n=1; 0.01%) were rare. Mean ages were 61.4 (candidiasis), 55 (paracoccidioidomycosis), 49.6 (actinomycosis), and 29.6 (syphilis). Female predominance occurred in candidiasis and actinomycosis, and male predominance in paracoccidioidomycosis and syphilis. In candidiasis, clinical hypotheses frequently included carcinoma or potentially malignant disorders (50.5%), with final diagnoses mainly epithelial dysplasia (31%) and hyperkeratosis (27.6%). Paracoccidioidomycosis was often suspected as carcinoma (52.6%), while actinomycosis was associated with cystic lesions (66.6%).
Conclusion: Oral candidiasis is frequently associated with epithelial dysplasia and hyperkeratosis, requiring infection control before definitive diagnosis. Paracoccidioidomycosis often mimics carcinoma, and actinomycosis should be considered in persistent cystic lesions. Other infections are uncommon.
Funding: São Paulo Research Foundation (FAPESP), grant nº 2025/01702-6.

Autor 1:  Luís Henrique CARDOSO

E-mail 1:  [email protected]

Autor 2:   Thaís Cachuté PARADELLA

E-mail 2:  [email protected]

Autor 3 :  Ana Lia ANBINDER

E-mail 3:  [email protected]