NUMERO: #20250530

Título: FATAL SQUAMOUS CELL CARCINOMA THE BURDEN OF DELAY IN TREATMENT

Nome do Apresentador: Júlio César Rodrigues MARTINS

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Estomatologia

Resumo: We report a case admitted outpatient care with a facial swelling and pain in a 52 years old female patient. Clinically manifested as a tumoral mass in the vestibular mucosa of the left maxilla with a granulomatous appearance, sessile base and irregular, telangiectatic surface. Preoperative exams included coagulation tests, fasting blood glucose and blood count. The patient underwent biopsy surgery, during the procedure was performed a triple-site incisional biopsy. Microscopic sections revealed oral mucosa fragment with presence of atypical mitoses, hyperchromatic cells with loss of nucleocytoplasmic ratio, keratin pearls, islets and epithelial cords in perivascular and perineural invasion. Immunohistochemistry revealed P53 +, P16 and Ki-67 on 60 to 70% of cells, staging revealed cT4cN3bcM0, confirming diagnosis of moderately differentiated stage IVB squamous cell carcinoma. There was a delay in oncological treatment, hemimaxillectomy and bilateral neck dissection were performed. The patient passed away 6 months after the initial diagnosis.

Autor 1:  Júlio César Rodrigues MARTINS

E-mail 1:  [email protected]

Autor 2:   Larissa Macedo Braule PINTO

E-mail 2:  [email protected]

Autor 3 :  Matheus Mesquita da Silva MELLO

E-mail 3:  [email protected]

Autor 4:  Henry Daniel Castro de OLIVEIRA

E-mail 4:  [email protected]

Autor 5:  Maria Carolina Coutinho Xavier SOARES

E-mail 5:  [email protected]

Autor 6:  Lioney Nobre CABRAL

E-mail 6:  [email protected]

Autor 7:  Tiago Novaes PINHEIRO

E-mail 7:  [email protected]