NUMERO: #20250493

Título: CONSERVATIVE MANAGEMENT OF CENTRAL GIANT CELL GRANULOMA WITH INTRALESIONAL CORTICOSTEROIDS: A CASE REPORT

Nome do Apresentador: Constância Cunha de LIMA

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Cirurgia e traumatologia bucomaxilofacial

Resumo: Central Giant Cell Granuloma (CGCG) of the jaws is a benign osteolytic lesion with sometimes aggressive behavior. This case report describes an 18-year-old male with no relevant medical history, presenting with a painless swelling in the left paranasal region. CT imaging revealed a hypodense lesion of approximately 18 mm between teeth 22 and 23, causing root displacement. An incisional biopsy showed multinucleated osteoclast-like giant cells in a vascularized fibrous stroma. Normal parathyroid hormone levels ruled out systemic causes, confirming CGCG. Conservative treatment with 25 intralesional corticosteroid injections reduced the lesion to 8 mm, after which curettage was performed. The patient remains under follow-up with satisfactory bone regeneration. This case supports the use of intralesional corticosteroid therapy as a conservative approach for CGCG, potentially reducing surgical morbidity and improving outcomes.

Autor 1:  Constância Cunha de LIMA

E-mail 1:  [email protected]

Autor 2:   Ana Júlia de Paula CANDEIA

E-mail 2:  [email protected]

Autor 3 :  Matheus Oliveira de SALES

E-mail 3:  [email protected]

Autor 4:  Gustavo França SILVA

E-mail 4:  [email protected]

Autor 5:  Gleyson Kleber do AMARAL-SILVA

E-mail 5:  [email protected]

Autor 6:  Ellen Cristina GAETTI-JARDIM

E-mail 6:  [email protected]

Autor 7:  Gustavo Silva PELISSARO

E-mail 7:  [email protected]