NUMERO: #20250464

Título: PHOTODYNAMIC THERAPY IN ORAL LESIONS OF A PATIENT WITH ACUTE LYMPHOBLASTIC LEUKEMIA

Nome do Apresentador: Jheniffer Genova COSTA

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Estomatologia

Resumo: Acute lymphoblastic leukemia (ALL) is the most common childhood cancer. Chemotherapy-induced immunosuppression often leads to oral complications, including opportunistic infections that can delay treatment and affect quality of life. A 13-year-old male patient undergoing treatment for acute lymphoblastic leukemia developed ulcerations on the lower lip. Clinical examination revealed neutropenia (1,123 leukocytes/mm³; 125 segmented neutrophils/mm³) and multiple deep ulcerations on the lower lip and chin. These ulcerations were irregular in shape, presented with purulent discharge for five days, and appeared after the completion of a chemotherapy cycle (MTX 2 g/m²/day; leucovorin 12 mg/m²). Based on the clinical features, an opportunistic infection was the proposed diagnosis, and photodynamic therapy was initiated daily using methylene blue and a red laser at 2 J/cm². A culture of the lip lesions was requested and later revealed the presence of Prevotella intermedia. After 20 sessions, the lesions were fully healed.

Autor 1:  Jheniffer Genova COSTA

E-mail 1:  [email protected]

Autor 2:   Daniella Moraes ANTUNES

E-mail 2:  [email protected]

Autor 3 :  Ellen Cristina Gaetti JARDIM

E-mail 3:  [email protected]

Autor 4:  Gabriela Moura CHICRALA

E-mail 4:  [email protected]

Autor 5:  Gleyson Kleber do Amaral SILVA

E-mail 5:  [email protected]

Autor 6:  Douglas Magno GUIMARÃES

E-mail 6:  [email protected]