NUMERO: #20250326

Título: DIAGNOSTIC APPROACH TO DARIER DISEASE THROUGH ORAL LESIONS: A CASE REPORT

Nome do Apresentador: Luana Darc Diafilos TEIXEIRA

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Estomatologia

Resumo: Darier disease (DD) is a rare disorder of keratinization that primarily affects the skin, with
occasional involvement of the oral mucosa. A 54-year-old male was referred for evaluation due to
white lesions in his mouth, which his dentist noticed. The patient reported hypertension and skin
allergies, presenting multiple small, firm, reddish-brown papules on the chest and back. Intraoral
examination revealed multiple non-removable, asymptomatic, white, flat-topped papules affecting
the palate and gingiva. An incisional biopsy of the palate was performed, and histopathological
analysis revealed acantholytic dyskeratosis. The clinical and microscopic findings together
supported the diagnosis of DD. Upon further examination, nail dystrophy was also observed. The
patient was referred to a dermatologist for evaluation and management of the skin lesions. While
oral lesions associated with DD typically do not require specific treatment, dentists play a crucial
role in diagnosis, as oral lesions can serve as a key indicator of the condition.

Autor 1:  Luana Darc Diafilos TEIXEIRA

E-mail 1:  [email protected]

Autor 2:   Jefferson da Rocha TENÓRIO

E-mail 2:  [email protected]

Autor 3 :  Claudia Maria PEREIRA

E-mail 3:  [email protected]

Autor 4:  Juliana de Noronha Santos NETTO

E-mail 4:  [email protected]

Autor 5:  Aline Corrêa ABRAHÃO

E-mail 5:  [email protected]

Autor 6:  Mário José ROMAÑACH

E-mail 6:  [email protected]

Autor 7:  Michelle AGOSTINI

E-mail 7:  [email protected]