NUMERO: #20250324

Título: HISTOPLASMOSIS WITH ORAL MANIFESTATIONS: REPORT OF THREE CASES

Nome do Apresentador: Hugo Sobrinho BUENO

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Estomatologia

Resumo: Histoplasmosis may resemble other oral infections or neoplasms, making diagnosis challenging. We report three cases with oral involvement. Case 1: a 49-year-old HIV-positive white male with an ulcer on the buccal gingiva of tooth 36 and multiple lesions on the maxillary ridge and right hard palate (40-day evolution). Case 2: a 52-year-old white male with a painful ulcer on the tongue tip (60 days). Case 3: a 48-year-old white male with an ulcer on the lower labial mucosa and multiple ulcers on the left buccal mucosa (1-month evolution). Differential diagnoses included paracoccidioidomycosis, histoplasmosis, and squamous cell carcinoma. Incisional biopsies revealed granulomatous inflammation and small PAS-positive yeasts, confirming histoplasmosis. All patients were referred to infectious disease specialists and remain under follow-up. These cases underscore the importance of dental professionals in recognizing oral signs of systemic infections, enabling early diagnosis and appropriate referral.

Autor 1:  Hugo Sobrinho BUENO

E-mail 1:  [email protected]

Autor 2:   Beatriz Pontim PISTOLATO

E-mail 2:  [email protected]

Autor 3 :  Monica Moreno de CARVALHO

E-mail 3:  [email protected]

Autor 4:  Marcio Cesar Reino GAGGINI

E-mail 4:  [email protected]

Autor 5:  Luciana Estevam SIMONATO

E-mail 5:  [email protected]