NUMERO: #20250304

Título: PROGRESSIVE DISSEMINATED HISTOPLASMOSIS IN AN HIV-POSITIVE PATIENT ADMITTED TO A REFERENCE HOSPITAL.

Nome do Apresentador: Lucas de Oliveira TROVISCO

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Estomatologia

Resumo: A 51-year-old male patient, HIV-positive with AIDS, thrombocytopenic, and hepatopathic, was admitted to a tropical diseases reference hospital for management of immunosuppression, presents multiple oral lesions on the dorsal tongue with a hairy appearance and coloration alternating between blackish and yellowish-white, as well as whitish ulcerations with erythematous margins on the tongue and on the buccal mucosa, the latter exhibiting markedly elevated margins, an irregular surface, and a slightly hardened consistency. No history of drug abuse. An incisional biopsy using a punch was performed on the left lingual body due to suspicion of malignancy. Histopathological examination revealed disorganized connective tissue with dense, diffuse lymphohistiocytic infiltrate, accompanied by numerous small yeast-like structures that stained positive with PAS and Gomori-Grocott, consistent with the micronidia of Histoplasma capsulatum, establishing a diagnosis of progressive disseminated histoplasmosis. Patient began systemic antifungal therapy, showed clinical improvement and remains under follow-up of 5 months to date.

Autor 1:  Lucas de Oliveira TROVISCO

E-mail 1:  [email protected]

Autor 2:   João Victor de Souza LOPES

E-mail 2:  [email protected]

Autor 3 :  Mariah Burlamaqui GUIMARÃES

E-mail 3:  [email protected]

Autor 4:  Henry Daniel Castro de OLIVEIRA

E-mail 4:  [email protected]

Autor 5:  Mary Elsa Cesar ALECRIM

E-mail 5:  [email protected]

Autor 6:  Tiago Novaes PINHEIRO

E-mail 6:  [email protected]

Autor 7:  Lioney Nobre CABRAL

E-mail 7:  [email protected]