NUMERO: #20250294

Título: LONG-TERM OBSERVATION OF ORAL LICHEN PLANUS WITH LATE MALIGNANT TRANSFORMATION: A CASE REPORT

Nome do Apresentador: Michele di BENEDETTO

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Estomatologia

Resumo: Oral lichen planus (OLP) is a chronic mucocutaneous disease with malignant potential. We report the case of a 38-year-old man diagnosed with reticular and erosive OLP affecting the buccal mucosa and skin. The patient was maintained under six-month follow-up, returning mainly during symptomatic episodes. The lesions remained clinically stable and were treated with topical corticosteroids when symptomatic. After 25 years of follow-up, he reported persistent pain in the left buccal mucosa, where an atrophic lesion was biopsied and revealed OLP with severe epithelial dysplasia. One year later, a new biopsy at the same site, confirmed squamous cell carcinoma. The patient underwent surgical resection and radiotherapy; however, regional metastases developed, and he died within a year. This case highlights the importance of long-term monitoring, early recognition of high-risk lesions, and strict documentation, even in cases with prolonged clinical stability.

Autor 1:  Michele di BENEDETTO

E-mail 1:  [email protected]

Autor 2:   Lukas Mendes de ABREU

E-mail 2:  [email protected]

Autor 3 :  Izabel Regina Fischer Rubira-Bullen

E-mail 3:  [email protected]

Autor 4:  Cleverson Teixeira Soares

E-mail 4:  [email protected]

Autor 5:  Paulo Sérgio da Silva Santos

E-mail 5:  [email protected]

Autor 6:  Cássia Maria Fischer RUBIRA

E-mail 6:  [email protected]

Autor 7:  Camila Lopes Cardoso

E-mail 7:  [email protected]