NUMERO: #20250256

Título: EXUBERANT NODULAR FASCIITIS ON LOWER LIP: A CASE REPORT

Nome do Apresentador: Rayana Longo BIGHETTI-TREVISAN

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Patologia Oral

Resumo: Nodular fasciitis (NF) is a self-limiting proliferation of fibroblasts and myofibroblasts that has been reported in different body sites, but the occurrence in oral cavity is rare. A 48-year-old male patient presented with a large painless submucosal nodule on the left side of lower lip mucosa with seven months of evolution. The nodule was soft and measured approximately 3 cm. The lesion was excised, and the histopathological examination demonstrated a proliferation of spindle cells, mostly fibroblasts and myofibroblasts, with pale-colored oval nuclei, arranged a storiform pattern with short irregular bundles and fascicles, in addition to myxoid areas. Also, hyaline fibrosis and scattered erythrocytes were noted. The immunohistochemistry demonstrated positivity for HHF35, SMA and calponin and negativity for desmin, h-caldesmon and CD34. The Ki67 index was less than 5%. Based on this, the diagnosis of NF was confirmed. The patient has been followed up for 2 months with no recurrence.

Autor 1:  Rayana Longo BIGHETTI-TREVISAN

E-mail 1:  [email protected]

Autor 2:   Hélen Kaline Farias BEZERRA

E-mail 2:  [email protected]

Autor 3 :  Paulo Esteves Pinto FARIA

E-mail 3:  [email protected]

Autor 4:  Pablo Agustin VARGAS

E-mail 4:  [email protected]

Autor 5:  Yara Teresinha Corrêa SILVA-SOUSA

E-mail 5:  [email protected]