NUMERO: #20250190

Título: INTRAOSSEOUS MYOFIBROMA OF THE MANDIBLE: AN UNUSUAL CASE REPORT

Nome do Apresentador: Matheus Antoni da Silva COSTA

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Patologia Oral

Resumo: Myofibroma is a rare benign mesenchymal tumor arising from the abnormal proliferation of myofibroblasts, with intraosseous involvement of the jaws being uncommon. We present the case of a 16-year-old female patient who developed pain and swelling in the right mandibular angle nine months after the extraction of the lower right third molar. Intraoral examination revealed a nodular mass with a fibrous consistency. Computed tomography (CT) imaging demonstrated a hypodense lesion with indistinct borders, cortical expansion, and areas of cortical perforation. Histopathological analysis of the surgically excised lesion revealed a proliferation of spindle-shaped and round neoplastic cells arranged in a fascicular pattern within a collagenized fibrous stroma. The neoplastic cells exhibited small, rounded nuclei and eosinophilic cytoplasm. Immunohistochemical staining demonstrated strong positivity for α-SMA. Based on these findings, a diagnosis of myofibroma was established. The patient remains under follow-up, with no signs of recurrence after six months.

Autor 1:  Matheus Antoni da Silva COSTA

E-mail 1:  [email protected]

Autor 2:   Tulio Del Conte VALCANAIA

E-mail 2:  [email protected]

Autor 3 :  Nicole LONNI

E-mail 3:  [email protected]

Autor 4:  Thiago Pires CLAUDIO

E-mail 4:  [email protected]

Autor 5:  Caroline ALFAIA SILVA

E-mail 5:  [email protected]

Autor 6:  Ricardo Luiz Cavalcanti de ALBUQUERQUE-JÚNIOR

E-mail 6:  [email protected]

Autor 7:  Rogério GONDAK

E-mail 7:  [email protected]