NUMERO: #20250187

Título: MESENCHYMAL CHONDROSARCOMA AFFECTING THE MAXILLA: A RARE CASE REPORT

Nome do Apresentador: Isadora Koepp DARELLA

Categoria do Trabalho: Apresentação oral de casos clínicos (AOC)

Área Temática: Patologia Oral

Resumo: Mesenchymal chondrosarcoma (MCS) is a high-grade, biphasic, malignant cartilaginous tumor that predominantly affects the craniofacial region of young adults. A 24-year-old man was referred for evaluation upon an incidental radiographic finding of a well-defined unilocular mixed radiolucent-radiopaque lesion associated with the right maxillary third molar. Under the clinical impression of a dentigerous cyst, an excisional biopsy was performed under local anesthesia. Microscopic analysis revealed a diffuse neoplasm composed of primitive undifferentiated round cells arranged in a perivascular hemangiopericytoma-like pattern, admixed with scarce islands of well-differentiated hyaline cartilage. The tumor cells expressed diffuse positivity for CD99, SOX9, NKX3-1, and D2-40, while S100 expression was restricted to the hyaline cartilage component. The cell proliferation index measured by Ki-67 was 5%. The final diagnosis of MCS was established. The patient was subsequently referred to oncologic treatment. MCS represents a rare malignancy that may mimic odontogenic lesions when occurring in the jaws.

Autor 1:  Isadora Koepp DARELLA

E-mail 1:  [email protected]

Autor 2:   Odinei Gustavo Pontes FREITAS

E-mail 2:  [email protected]

Autor 3 :  Ana Luiza Oliveira Corrêa ROZA

E-mail 3:  [email protected]

Autor 4:  Hélen Kaline Farias BEZERRA

E-mail 4:  [email protected]

Autor 5:  Talita de Carvalho KIMURA

E-mail 5:  [email protected]

Autor 6:  Clóvis Antonio Lopes PINTO

E-mail 6:  [email protected]

Autor 7:  Pablo Agustin VARGAS

E-mail 7:  [email protected]