NUMERO: #20250129

Título: SPOTTING ORAL SIGNS WITH SYSTEMIC IMPACT: THE DENTISTS ESSENTIAL ROLE IN IDENTIFYING A RARE CASE OF AMYLOIDOSIS

Nome do Apresentador: Lucas Freitas CARNEVALI

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Patologia Oral

Resumo: Amyloidosis is a rare disease characterized by the accumulation of abnormal proteins in tissues. Systemic amyloidosis is often associated with underlying diseases. We report the case of a patient with macroglossia and granulomatous nodules with yellowish pearls on the tongue and buccal mucosa, accompanied by burning sensations and muscle retraction symptoms. Systemic symptoms included swollen hands with non-pitting edema, a "shoulder pad sign" lesion, and scleroderma-like lesions on the chest. An incisional biopsy of the tongue showed Congo-red greenish-yellow amorphous hyaline material in the connective tissue under polarized light, confirming the diagnosis of amyloidosis. The patient was referred to a rheumatologist. Proteomic analysis revealed light-chain (AL) amyloidosis subtype but no underlying cause was identified after thorough systemic investigation. The patient started chemotherapy treatment and is under close follow-up. This case describes a rare case of idiopathic primary amyloidosis diagnosed through oral manifestations.

Autor 1:  Lucas Freitas CARNEVALI

E-mail 1:  [email protected]

Autor 2:   Juliana MOTA Siqueira

E-mail 2:  [email protected]

Autor 3 :  Larissa ANTUNES de Jesus

E-mail 3:  [email protected]

Autor 4:  Renan Rodrigues Neves Ribeiro do NASCIMENTO

E-mail 4:  [email protected]

Autor 5:  Fabio DAUMAS Nunes

E-mail 5:  [email protected]

Autor 6:  Vivian Petersen WAGNER

E-mail 6:  [email protected]