NUMERO: #20250075

Título: Chronic hyperplastic candidiasis, nodular type: an immunohistochemical study.

Nome do Apresentador: Nathalia Caetano MARQUES

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Estomatologia

Resumo: Chronic hyperplastic candidiasis (CHC) is a distinctive clinical subtype of oral candidiasis, which presents as whitish oral plaques, frequently at the labial commissure. Nodular type, CHC is a rare subgroup, which can simulate clinically other infections, even neoplasms and malignancy. A 44-year-old female presented with a nodular lesion on the tongue three years ago. Medical history was noncontributory and infectious disease serology was negative. The main clinical hypothesis was condyloma acuminatum. After excisional biopsy, microscopy showed a florid epithelial proliferation and intense lymphoplasmacytic infiltrate infiltrating muscle bundles, along with foci of candidiasis. Immunohistochemistry revealed predominance of T cells over B cells, numerous intervening granulocytes and macrophages, hyperplasia of Largerhans cells, and foci of plasma cells. Nodular type, CHC is rare and diagnostically challenging, requiring histopathological confirmation. Stomatology follow-up appointments are essential for monitoring clinical progression.

Autor 1:  Nathalia Caetano MARQUES

E-mail 1:  [email protected]

Autor 2:   Mariana Paravani PALAÇON

E-mail 2:  [email protected]

Autor 3 :  Marcelo Borges MARQUES

E-mail 3:  [email protected]

Autor 4:  Thales Peres Candido MOREIRA

E-mail 4:  [email protected]

Autor 5:  Anderson Tangerino Ferreira DA SILVA

E-mail 5:  [email protected]

Autor 6:  Andreia BUFALINO

E-mail 6:  [email protected]

Autor 7:  Jorge Esquiche LEÓN

E-mail 7:  [email protected]