NUMERO: #20250073

Título: CLEAR CELL VARIANT OF MUCOEPIDERMOID CARCINOMA: A DIGNOSTIC CHALLENGE IN SALIVARY GLAND PATHOLOGY

Nome do Apresentador: Marco Túlio Leandro RIBEIRO

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Oncologia

Resumo: Mucoepidermoid carcinoma (MEC) is the most common malignant neoplasm of the salivary glands, however, its clear cell variant (cMEC) is infrequently reported. A 36-year-old woman presented with a well-circumscribed, painless, reddish nodule measuring 1.5 cm on the left side of the hard palate, with fibroelastic consistency and superficial ulceration. Cone-beam computed tomography revealed a hyperdense lesion without adjacent bone involvement. Based on the clinical presentation, the main diagnostic considerations included pleomorphic adenoma and mucoepidermoid carcinoma. An incisional biopsy was performed, and histopathological and immunohistochemical findings suggested an unspecified salivary gland adenocarcinoma. The patient was referred to an oncology center, where surgical excision was performed. Definitive histopathological evaluation lead to the diagnosis of cMEC. Postoperative management included rehabilitation with a prosthetic obturator, and spontaneous closure of a buccosinusal communication was observed. The patient remains under regular medical and dental follow-up, showing excellent clinical progress with no evidence of recurrence to date.

Autor 1:  Marco Túlio Leandro RIBEIRO

E-mail 1:  [email protected]

Autor 2:   Regina Maria Holanda de MENDONÇA

E-mail 2:  [email protected]

Autor 3 :  João Paulo Gonçalves PAIVA

E-mail 3:  [email protected]

Autor 4:  Brenda Corrêa SANTOS

E-mail 4:  [email protected]

Autor 5:  Daniel Lobato Ferreira FERRAZ

E-mail 5:  [email protected]

Autor 6:  Pablo Agustin VARGAS

E-mail 6:  [email protected]

Autor 7:  Marcio Ajudarte LOPES

E-mail 7:  [email protected]