NUMERO: #20250040

Título: CLINICOPATHOLOGICAL ANALYSIS OF ORAL AND PERIORAL KERATOACANTHOMA: A SYSTEMATIC REVIEW

Nome do Apresentador: Carolina Louzada Menna BARRETO

Categoria do Trabalho: Painel de Revisões narrativas ou sistemáticas (PRN)

Área Temática: Patologia Oral

Resumo: Objective: To systematically review the literature on clinicopathological features of keratoacanthoma (KA) in the oral and perioral region.
Study design: The review protocol was registered under the number CRD42022323274. Electronic searches were conducted in four databases with a specific search strategy using MeSH and free terms.
Results: 60 studies reporting 73 cases of KA were included in this systematic review. KA affects more men with a mean age of 49.09 years old. Sun-exposed areas of the lower lip were the most common anatomical location of the perioral lesions (38.35%) and not specified oral mucosa in intra-oral lesions (9.58). The most frequent clinical presentation of the perioral lesions was of an ulcerated nodule (36.23) and intra-orally of an papule (11.59) or nodule (11.59). Incisional biopsies were the commonest procedure for the diagnosis, showing common histopathological findings. Surgical excision was the treatment of choice in the majority of cases (45.71%). A low recurrence rate (6.89%) was seen in a mean follow-up time of 20.54 months.
Conclusion: KA affects commonly the sun-exposed areas of men in their sixth decade of life. Given the similarity of squamous cell carcinoma, it is important to study KA to help clinicians with the correct diagnose and treatment.

Autor 1:  Carolina Louzada Menna BARRETO

E-mail 1:  [email protected]

Autor 2:   Laura Borges KIRSCHNICK

E-mail 2:  [email protected]

Autor 3 :  Lauren Frenzel SCHUCH

E-mail 3:  [email protected]

Autor 4:  Fabio Muradás GIRARDI

E-mail 4:  [email protected]

Autor 5:  Márcio Ajudarte LOPES

E-mail 5:  [email protected]

Autor 6:  Manoela Domingues MARTINS

E-mail 6:  [email protected]