NUMERO: #20250035

Título: PLEXIFORM SCHWANNOMA OF THE TONGUE: AN UNUSUAL CASE REPORT

Nome do Apresentador: André Goulart POLETTO

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Patologia Oral

Resumo: Plexiform schwannoma is a rare variant of schwannoma, characterized by a multinodular growth pattern. We report the case of a 25-year-old woman who presented with a well-circumscribed nodular mass on the dorsal surface of the tongue, measuring 1.5 cm, with a 12-month history. Based on clinical characteristics, the initial hypothesis was lipoma. An excisional biopsy was performed, and histopathological examination revealed multiple nodules of benign neural proliferation, composed of compact spindle-shaped cells (Antoni A pattern) with tapered nuclei and elongated cytoplasm, arranged in a palisading pattern, forming Verocay bodies. Hypocellular, loosely arranged, and myxoid areas (Antoni B pattern) were also observed. The nodules were surrounded by a thin fibrous capsule, and vascular walls exhibited thickening and hyalinization. Immunohistochemical analysis showed strong S-100 protein expression in tumor cells, while CD34 was negative. The final diagnosis was plexiform schwannoma. The patient remains under follow-up with no signs of recurrence.

Autor 1:  André Goulart POLETTO

E-mail 1:  [email protected]

Autor 2:   Bernardo OLSSON

E-mail 2:  [email protected]

Autor 3 :  Gustavo Davi RABELO

E-mail 3:  [email protected]

Autor 4:  Túlio ROSA

E-mail 4:  [email protected]

Autor 5:  Elena Riet Correa RIVERO

E-mail 5:  [email protected]

Autor 6:  Ricardo Luiz Cavalcanti de ALBUQUERQUE-JUNIOR

E-mail 6:  [email protected]

Autor 7:  Rogério GONDAK

E-mail 7:  [email protected]