NUMERO: #20250016

Título: PRIMARY XANTHOMA IN THE MANDIBLE: A CASE REPORT

Nome do Apresentador: Victor Alexandre Felicio TRANCOSO

Categoria do Trabalho: Painel de caso clínico (PCC)

Área Temática: Cirurgia e traumatologia bucomaxilofacial

Resumo: Primary intraosseous xanthoma affecting the jaws is an extremely rare entity classified within the broad group of histiocytic diseases. We report a case of a 47-year-old female who presented with complaints of pain and swelling in the right mandibular ramus, with a six-month history of progression. On intraoral examination, swelling was observed in the retromolar region and the right mandibular ramus. Computed tomography showed a multilocular hypodense lesion with a destructive appearance, extending throughout the mandibular ramus and causing cortical bulging and thinning. An incisional biopsy was performed, revealing numerous histiocytes within a myxoinflammatory background, with positivity for CD68 and negativity for S-100, confirming the diagnosis of xanthoma. Laboratory tests for cholesterol and triglycerides were within normal limits. Surgical excision of the lesion was performed via a submandibular approach, followed by curettage and peripheral osteotomy. The histopathological examination of the final specimen confirmed the diagnosis.

Autor 1:  Victor Alexandre Felicio TRANCOSO

E-mail 1:  [email protected]

Autor 2:   Fernando Melhem-Elias

E-mail 2:  [email protected]

Autor 3 :  Aloísio Souza Felipe-Silva

E-mail 3:  [email protected]

Autor 4:  Shajadi Carlos Pardo Kaba

E-mail 4:  [email protected]